Figure 1From: Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical studyPhotomicrographs of colonic tissue immunohistochemically stained for PSCA. Intense staining can be seen in a crypt neuroendocrine cell (1A, arrow). Colonocytes show little or no staining across all stages of the adenoma-carcinoma sequence. No changes in intensity or topographic distribution of PSCA expression were observed between normal mucosa (1B), adenomatous tissue displaying low grade epithelial dysplasia (1C), and invasive carcinoma (1D).Back to article page