Table 1 Characteristic differences in expression of 14-3-3 protein isoforms in the different stages of follicular development as observed by immunohistochemical staining of adult mouse ovarian sections
From: Expression of 14-3-3 protein isoforms in mouse oocytes, eggs and ovarian follicular development
Feature | Isoform | Stage of Ovarian Follicle | ||
|---|---|---|---|---|
| Â | Â | Secondary | Early Antral | Graafian |
Expression in zonae pellucidae around oocytes | 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ | ++ + ++ + - ++ ++ | ++ + ++ + - ++ ++ | ++ + ++ - - ++ ++ |
Prominent lack of expression in peripheral mural granulosa cells | 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ | Yes Yes Yes No Yes Yes Yes | Yes No No No No No No | Yes Yes Yes No No Yes Yes |
Marked accumulation in granulosa cells surrounding the antrum | 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ | Yes Yes No No No No Yes | Yes Yes Yes Yes Yes Yes Yes | |