Figure 5

Schematic illustrations of full-length CEA and novel isoforms. Each motif (according to http://www.carcinoembryonic-antigen.de/index.html) is indicated as follows: N, amino-terminal IgV-like domains; A/B, IgC-like domains; lollipop, N-glycosylation sites predicted with consensus sequences (N-X-S/T, X ≠ P); arrowhead, glycosylphosphatidylinositol (GPI) linkage to the cell membrane. The location of peptides identified by LC-MS/MS analysis are indicated in red.