Table 1 Allele and genotype frequencies of the APOE , MTHFR and ACE polymorphisms and HWE in the Zambian population (n = 116)

APOE

p = 0.456

Ε2

0.14

Ε2Ε2

0

1.9

X2 = 4.684

Ε3

0.6

Ε3Ε3

32.8

35.4

Ε4

0.27

Ε4Ε4

7.8

7.1

Ε2Ε3

21.6

16.4

Ε2Ε4

6

7.4

Ε3Ε4

31.9

31.8

MTHFR C677T

p = 0.540

C

0.91

CC

82.8

83.5

X2 = 1.233

T

0.09

CT

17.2

15.7

TT

0

0.74

ACE D/I

p = 0.005

D

0.14

DD

5

1.9

X2 = 10.472

I

0.86

ID

17.2

23.8

II

77.6

74.3