Skip to main content

Table 1 Association between SNPs and DAD in DS

From: Genetic variants conferring susceptibility to Alzheimer’s disease in the general population; do they also predispose to dementia in Down’s syndrome

Nearest gene

SNP

Risk allele

Hazard ratio

SE

p-value

CR1

rs3818361

A

1.10

0.17

0.59

BIN1

rs744373

G

1.16

0.16

0.36

CD2AP

rs9349407

C

0.99

0.15

0.93

EPHA1

rs11767557

T

1.03

0.16

0.86

CLU

rs1532278

C

1.05

0.13

0.69

MS4A6A

rs610932

G

1.03

0.15

0.83

PICALM

rs561655

A

0.67

0.14

5.89 × 10-3

ABCA7

rs3764650

G

1.09

0.29

0.76

CD33

rs3865444

C

0.83

0.15

0.22

Genetic risk score

-

–

0.97

0.06

0.66

  1. Covariates included in the analyses were sex, intellectual disability and APOE genotype.
Back to article page

BMC Research Notes

ISSN: 1756-0500

Contact us