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Table 2 Detection of persistent low avidity HPV16 or HPV18 antibodies at month 7 stratified by smoking status

From: Impact of smoking on the quantity and quality of antibodies induced by human papillomavirus type 16 and 18 AS04-adjuvanted virus-like-particle vaccine – a pilot study

 

Low avidity (= < 40%)

High avidity (>40%)

OR, 95% CI

HPV16

   

Non-smokers (n = 55)

4 (31%)

51 (57%)

1

Smokers (n = 48)

9 (69%)

39 (43%)

2.9 (0.8-10.3)

HPV18

Non-smokers (n = 55)

1 (33%)

54 (54%)

1

Smokers (n = 48)

2 (67%)

46 (46%)

2.8 (0.2-31.6)

HPV16/18

Non-smokers (n = 55)

5 (31%)

50 (57%)

1

Smokers (n = 48)

11 (69%)

37 (43%)

3.0 (1.0*-9.3)

  1. *Exact value = 0.95, and 40% is the cut-off of low avidity.