Table 2 Baseline characteristics of patients
From: Procalcitonin as a prognostic marker for sepsis: a prospective observational study
Characteristics | All patients (n = 54) | Alive (n = 31) | Dead (n = 23) | p-value |
|---|---|---|---|---|
Age (years) | 50.7 ± 18.7 | 50.5 ± 18.3 | 50.9 ± 19.4 | 0.94 |
Male sex | 30 (55%) | 18 (58%) | 12 (52%) | 0.66 |
ARDS | 22 (41%) | 10 (32%) | 12 (52%) | 0.14 |
Renal dysfunction | 31 (57%) | 14 (45%) | 17 (74%) | 0.03 |
Mean BP (mm hg) | 78.3 ± 13.7 | 82.3 ± 14.06 | 72.9 ± 11.5 | 0.01 |
Temperature (°F) | 100.2 ± 1.5 | 99.9 ± 1.2 | 100.5 ± 1.8 | 0.17 |
TLC (/cu mm) | 17900 (15200–24500) | 17800 (14400–24500) | 19900 (16000–25500) | 0.24 |
Urea (mg/dL) | 65 (52–93) | 62 (49–75) | 76 (61–108) | 0.11 |
Creatinine (mg/dL) | 1.5 (0.8-2.4) | 1.00 (0.8-1.8) | 1.80 (0.9- 3.6) | 0.11 |
Prothrombin time (s) | 15.1 ± 4.2 | 13.7 ± 2.8 | 16.9 ± 5.2 | 0.005 |
Blood sugar (mg/dL) | 140.4 ± 63.8 | 138.5 ± 52.1 | 142.9 ± 78.1 | 0.80 |
pH | 7.2 ± 0.1 | 7.3 ± 0.13 | 7.25 ± 0.20 | 0.38 |
Bicarbonate (mmol/L) | 22.7 ± 10.1 | 25.5 ± 10.4 | 19.1 ± 8.4 | 0.02 |
Albumin (gm/dL) | 2.9 ± 0.6 | 3.0 ± 0.6 | 2.8 ± 0.8 | 0.25 |
Lactate (mmol/L) | 1.8 (0.8-3.2) | 1.2 (0.8-2.1) | 2.4 (1.3-4.3) | 0.01 |
Positive culture | 24 (44%) | 13 (42%) | 11 (48%) | 0.66 |
Positive blood culture | 8 (15%) | 5 (16%) | 3 (13%) | 0.75 |
Mechanical ventilation | 37 (63%) | 16 (52%) | 21 (91%) | 0.002 |
Duration of ICU stay | 5 (3–6) | 5 (4–6) | 4 (3–5) | 0.75 |
Duration of hospital stay | 10.9 ± 8.1 | 14.6 ± 6.1 | 5.1 ± 3.5 | 0.001 |
Procalcitonin (ng/mL) | 6.9 (3.6-19.2) | 5.4 (3.5-12.8) | 13.1 (6.3-42) | 0.008 |
CRP (mg/dL) | 17.6 ± 7.3 | 20.1 ± 7.4 | 21 ± 7.4 | 0.76 |
SOFA score (Day 1) | 8.3 ± 3.7 | 6.7 ± 3.4 | 10.5 ± 3.2 | 0.0001 |
APACHE II score (Day 1) | 24.7 ± 7.8 | 21.9 ± 7.1 | 28.6 ± 7.1 | 0.001 |
SAPS II score (Day 1) | 53.2 ± 16.8 | 47.0 ± 14.9 | 61.5 ± 15.8 | 0.001 |