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Table 3 Comparative sensitivity and specificity of rapid HBsAg kit using HBsAg ELISA as gold standard

From: Risk factors associated with hepatitis B exposure and the reliability of five rapid kits commonly used for screening blood donors in Ghana

Test kit

Sensitivity

Specificity

PPV

NPV

Youden's index

Kappa test

(95% CI)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

(%)

Wondfo

59.1(36.4 - 79.3)

99.3(95.7 - 100.0)

92.9(66.1 - 99.8)

93.4(87.8 - 96.9)

58.3(32.1 - 79.3)

68.7

Accul-Tell

54.5(32.2 - 75.6)

99.2(95.7 - 100)

92.3(64.0 - 99.8)

92.7(87.0 - 96.4)

53.8(27.9 - 75.6)

64.7

Care Rapid

54.5(32.2 - 75.6)

99.3(95.7 - 100)

92.3(64–99.8)

92.7(87.0 - 96.4)

53.8(27.9 - 75.6)

64.7

Core Tm

50(28.2 - 71.8)

98.4(94.5 - 99.8)

84.6(54.5 - 98.1)

92.0(86.1 - 95.9)

48.4(22.7 - 71.6)

58.3

Abon

50(28–71.8

99.2(95.7 - 100)

91.7(61.5 - 99.8)

92.0(86.2 - 96.0)

49.2(23.9 - 71.8)

60.6

  1. NPV: Negative Predictive Value, PPV: Positive Predictive Value.