White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection

Table 8 Associations between FA values and cognitive measures

Cognitive domain	Measure	AC	LALIC	CC genu	RALIC
Visual scanning speed	TMT trails A	−0.051	−0.288	−0.157	−0.114
Cognitive set-shifting	TMT trails B	−0.274	−0.409**	−0.289	−0.182
Fine motor speed	GP–DH	−0.338*	−0.468**	−0.475**	−0.384*
Fine motor speed	GP–NDH	−0.145	−0.465**	−0.410**	−0.318*
Sustained attention	RVP A′	0.364*	0.403*	0.335*	0.094
Verbal learning	CVLT-II total recall	0.235	0.419**	0.206	0.343*
Immediate recall	CVLT-II SDFR	0.234	0.376*	0.065	0.242
Delayed recall	CVLT-II LDFR	0.222	0.416**	0.098	0.184
Verbal recognition	CVLT-II recognition	0.055	0.247	0.086	0.229
Concept shifting	IED EDS errors	−0.122	−0.053	−0.280	0.052
Concept formation	IED Pre-EDS errors	−0.080	−0.089	−0.317*	−0.003

Numbers represent Pearson correlations between cognitive scores and FA values
Significant correlation * p < 0.05, ** p < 0.01
AC anterior commissure, LALIC left anterior limb of the internal capsule, CC corpus callosum, RALIC right anterior limb of the internal capsule, TMT trail making test, GP grooved pegboard, DH dominant hand, NDH non-dominant hand, RVP rapid visual information processing, CVLT-II California verbal learning test-II, SDFR short-delay free recall, LDFR long-delay free recall, IED intra-extra dimensional shift, EDS extradimensional

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