Table 2 Optimal efficacy, IC90 and IC50 of test extracts against promastigote form of the parasite
Concentration (µg/mL) | Test drugs | Controls | Parameter and statistics | ||||
|---|---|---|---|---|---|---|---|
Az | Rc | Az + Rc | Pentostam | AMB | F value | P value | |
Optimal efficacy (%) | 78 | 61.5 | 91.2 | 96.5 | 98 | 26.654 | 0.002 |
Concentration at optimal efficacy | 43.5 | 69.5 | 55.2 | 30.4 | 40.2 | 9.257 | 0.012 |
IC90 | – | – | 42 | 16.2 | 25.1 | 15.226 | 0.003 |
IC50 | 10.1 | 25.5 | 12.2 | 4.1 | 5.0 | 15.456 | 0.000 |