Table 1 Baseline demographic and disease characteristics of ITT patient population
Characteristic | Result (n = 162) |
|---|---|
Demographics | |
Age, years | 37.4 ± 9.8 |
Sex | |
Male, n (%) | 40 (24.7 %) |
Female, n (%) | 122 (75.3 %) |
Race | |
Caucasian, n (%) | 153 (94.4 %) |
Black, n (%) | 2 (1.2 %) |
Asian, n (%) | 2 (1.2 %) |
Other, n (%) | 5 (3.1 %) |
Education, total years completed | 14.9 ± 3.3 |
Disease characteristics | |
MS classification | |
Relapsing-remitting, n (%) | 156 (96.3 %) |
Secondary progressive, n (%) | 6 (3.7 %) |
Months since onset of MS symptoms | 53.3 ± 76.1 |
Months since MS diagnosis | 24.0 ± 57.6 |
Months since last relapse | 6.4 ± 9.5 |
Number of relapses since onset of MS symptoms, n (%) | |
0 | 6 (3.7 %) |
1 | 44 (27.2 %) |
2 | 55 (34.0 %) |
3 | 34 (21.0 %) |
4 | 12 (7.4 %) |
≥5 | 11 (6.8 %) |
Expanded disability status scale (EDSS) Score | 1.8 ± 1.3 |
Cognitive function | |
Symbol digit modalities test (SDMT) | 51.0 ± 13.1 |
Patients failing test, n (%) | 35 (22.9 %) |
Selective reminding test (SRT) | |
Long-term storage | 41.8 ± 15.5 |
Patients failing test, n (%) | 61 (40.4 %) |
Consistent long-term retrieval | 30.0 ± 15.8 |
Patients failing test, n (%) | 59 (39.1 %) |
3-second paced auditory serial addition test (PASAT) | 42.8 ± 11.4 |
Patients failing test, n (%) | 47 (31.3 %) |
Cognitively impaired (failing ≥2 of the above tests) | 67 (47.8 %) |