Fig. 5From: A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy The conditional expression of Pdxk in the Drosophila eye results in reduced ommatidia number and increased disruption of the eyes and is suppressed upon co-expression with Buffy. a Scanning electron micrographs when Pdxk is inhibited in the eye (I) GMR-Gal4/UAS-lacZ and (II) GMR-Gal4/Pdxk-RNAi. b The biometric analysis of the eyes indicated a slight decrease in mean ommatidia number and a higher percent disruption of the eye when compared to the control. c The co-expression of Pdxk-RNAi with α-synuclein-expression (I) UAS-α-synuclein; GMR-Gal4/UAS-lacZ and (II) UAS-α-synuclein; GMR-Gal4/Pdxk-RNAi. Biometric analysis of α-synuclein-expression and Pdxk inhibition in the developing eye revealed no significance in the number of ommatidia and the degree of ommatidial disruption. d Co-expression of Buffy with Pdxk-RNAi (I) UAS-Buffy; GMR-Gal4/UAS-lacZ and (II) UAS-Buffy; GMR-Gal4/Pdxk-RNAi. Biometric analysis showed restoration of the mean number of ommatidia and ommatidial disruption to control levels. Comparisons were determined by unpaired two-tailed T test (P < 0.05), error bars are SEM, n = 10 and asterisks represent statistical significanceBack to article page