From: Insulin resistance in a cohort of 5–15 year old children in urban Sri Lanka
4-a: Mean fasting serum insulin (pmol/l) | |||||||||
---|---|---|---|---|---|---|---|---|---|
5–10 years | 10–15 years | ||||||||
BMI tertile | BMI tertile | ||||||||
T1 | T2 | T3 | T1 | T2 | T3 | Total | |||
Birth weight tertile | T1 | 16.5 ± 8.6 | 20.5 ± 9.1 | 33.2 ± 16.6** | 23.1 ± 13.8 | 28.5 ± 29.4 | 35.8 ± 18.7 | 69.9 ± 34.0** | 43.9 ± 34.2 |
T2 | 21.9 ± 23.5 | 26.2 ± 25.6 | 40.9 ± 28.8 | 28.4 ± 26.3 | 19.7 ± 8.5 | 49.6 ± 92.5 | 72.6 ± 52.6 | 46.3 ± 65.2 | |
T3 | 14.3 ± 0.9 | 30.3 ± 33.3 | 47.6 ± 64.5* | 32.6 ± 46.2 | 23.4 ± 16.8 | 38.9 ± 30.6 | 56.6 ± 24.4** | 41.8 ± 28.2 | |
Total | 17.7 ± 14.8 | 25.6 ± 24.4 | 40.7 ± 43.3** | 24.4 ± 21.6 | 42.3 ± 60.4 | 66.1 ± 38.2** | |||
4-b: Mean 2 h OGTT serum insulin (pmol/l) | |||||||||
Birth weight tertile | T1 | 85.3 ± 73.6 | 98.1 ± 52.2 | 250.7 ± 220.4** | 143.1 ± 154.2 | 156.7 ± 141.1 | 261.5 ± 145.3 | 577.6 ± 465** | 320.3 ± 343.3 |
T2 | 75.2 ± 60.6 | 111.5 ± 60.0 | 211.2 ± 219.8* | 123.8 ± 130.7 | 173.8 ± 133.0 | 241.8 ± 267.9 | 636.8 ± 567.7** | 339.8 ± 405.4 | |
T3 | 58.9 ± 40.1 | 67.3 ± 48.3 | 230.4 ± 199.4** | 130.2 ± 152.8 | 118.7 ± 70.2 | 186.9 ± 141.5 | 318.3 ± 190.5** | 217.5 ± 166.2 | |
Total | 75.0 ± 62.7 | 94.0 ± 56.2 | 232.9 ± 208.3** | 154.8 ± 126.0 | 225.0 ± 199.0 | 512.5 ± 449.7** | |||
4-c: Mean HOMA IR values | |||||||||
Birth weight tertile | T3 | 0.44 ± 0.21 | 0.57 ± 0.30 | 0.95 ± 0.51** | 0.65 ± 0.42 | 0.81 ± 0.79 | 0.95 ± 0.46 | 2.1 ± 1.0* | 1.2 ± 1.0 |
T1 | 0.56 ± 0.48 | 0.80 ± 0.92 | 1.20 ± 0.94 | 0.82 ± 0.82 | 0.57 ± 0.27 | 1.42 ± 2.7 | 2.2 ± 1.7* | 1.35 ± 1.94 | |
T2 | 0.38 ± 0.05 | 0.85 ± 1.0 | 1.29 ± 1.70 | 0.89 ± 1.3 | 0.70 ± 0.53 | 1.2 ± 0.96 | 1.6 ± 0.71* | 1.2 ± 0.86 | |
Total | 0.47 ± 0.31 | 0.74 ± 0.80 | 1.1 ± 1.2* | 0.71 ± 0.60 | 1.22 ± 1.8 | 1.9 ± 1.2** |