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Table 4 Association between different measures of insulin sensitivity and birth and current BMI tertile groups for 5–10 and 10–15 year old age categories

From: Insulin resistance in a cohort of 5–15 year old children in urban Sri Lanka

4-a: Mean fasting serum insulin (pmol/l)

 

5–10 years

10–15 years

BMI tertile

BMI tertile

T1

T2

T3

 

T1

T2

T3

Total

Birth weight tertile

T1

16.5 ± 8.6

20.5 ± 9.1

33.2 ± 16.6**

23.1 ± 13.8

28.5 ± 29.4

35.8 ± 18.7

69.9 ± 34.0**

43.9 ± 34.2

T2

21.9 ± 23.5

26.2 ± 25.6

40.9 ± 28.8

28.4 ± 26.3

19.7 ± 8.5

49.6 ± 92.5

72.6 ± 52.6

46.3 ± 65.2

T3

14.3 ± 0.9

30.3 ± 33.3

47.6 ± 64.5*

32.6 ± 46.2

23.4 ± 16.8

38.9 ± 30.6

56.6 ± 24.4**

41.8 ± 28.2

Total

17.7 ± 14.8

25.6 ± 24.4

40.7 ± 43.3**

 

24.4 ± 21.6

42.3 ± 60.4

66.1 ± 38.2**

 

4-b: Mean 2 h OGTT serum insulin (pmol/l)

Birth weight tertile

T1

85.3 ± 73.6

98.1 ± 52.2

250.7 ± 220.4**

143.1 ± 154.2

156.7 ± 141.1

261.5 ± 145.3

577.6 ± 465**

320.3 ± 343.3

T2

75.2 ± 60.6

111.5 ± 60.0

211.2 ± 219.8*

123.8 ± 130.7

173.8 ± 133.0

241.8 ± 267.9

636.8 ± 567.7**

339.8 ± 405.4

T3

58.9 ± 40.1

67.3 ± 48.3

230.4 ± 199.4**

130.2 ± 152.8

118.7 ± 70.2

186.9 ± 141.5

318.3 ± 190.5**

217.5 ± 166.2

Total

75.0 ± 62.7

94.0 ± 56.2

232.9 ± 208.3**

 

154.8 ± 126.0

225.0 ± 199.0

512.5 ± 449.7**

 

4-c: Mean HOMA IR values

Birth weight tertile

T3

0.44 ± 0.21

0.57 ± 0.30

0.95 ± 0.51**

0.65 ± 0.42

0.81 ± 0.79

0.95 ± 0.46

2.1 ± 1.0*

1.2 ± 1.0

T1

0.56 ± 0.48

0.80 ± 0.92

1.20 ± 0.94

0.82 ± 0.82

0.57 ± 0.27

1.42 ± 2.7

2.2 ± 1.7*

1.35 ± 1.94

T2

0.38 ± 0.05

0.85 ± 1.0

1.29 ± 1.70

0.89 ± 1.3

0.70 ± 0.53

1.2 ± 0.96

1.6 ± 0.71*

1.2 ± 0.86

Total

0.47 ± 0.31

0.74 ± 0.80

1.1 ± 1.2*

 

0.71 ± 0.60

1.22 ± 1.8

1.9 ± 1.2**

 
  1. Comparison is made across different BMI tertiles within a single birth tertile
  2. When compared between different birth weight tertiles within the same BMI tertile, there were no significance in the difference
  3. Ranges of birth weight tertile distribution are; <10 years, 1.00–2.90, 2.91–3.25, 3.26–4.76 kg; ≥10 years, 1.00–2.80, 2.81–3.20, 3.25–4.25 kg
  4. * Significantly higher (p < 0.05) than the lowest value of the BMI tertiles
  5. ** Significantly higher (p < 0.05) than the lowest 2 values of the BMI tertiles