Table 4 Ingenuity pathway analysis of the 85 co-occurring genes
(a) Top molecules | |||
|---|---|---|---|
Genes | Description | Chromosome | Exp. value |
SAC3D1 | SAC3 domain containing 1 | 11q13.1 | 0.772 |
EIF3B | Eukaryotic translation initiation factor 3, subunit B | 7p22.3 | 0.692 |
Peptide deformylase (mitochondrial) | 16q22.1 | 0.680 | |
FKBP1A | FK506 binding protein 1A, 12 kDa | 20p13 | 0.661 |
TIMP2 | TIMP metallopeptidase inhibitor 2 | 17q25 | 0.586 |
RYR3 | Ryanodine receptor 3 | 15q14-q15 | 0.567 |
U2AF2 | U2 small nuclear RNA auxillary factor 2 | 19q13.42 | 0.558 |
B3GALT6 | UDP-Gal:betaGal beta 1, 3-galactosyltransferase polypeptide 6 | 1p36.33 | 0.543 |
CBX7 | Chromobox homolog 7 | 22q13.1 | 0.536 |
CDX19 | Cyclin-dependent kinase 19 | 6q21 | 0.523 |
(b) Top canonical pathways | ||
|---|---|---|
Name | P value | Ratio |
Insulin receptor signaling | 3.45E−03 | 3/139 (0.022) |
Protein kinase A signaling | 5.74E−03 | 4/327 (0.012) |
Clarin-mediated endocytosis signalling | 6.29E−03 | 3/172 (0/017) |
Spliceosomal cycle | 7.06E−03 | 1/10 (0.100) |
Calcium signaling | 7.93E−03 | 3/207 (0.014) |