Table 2 Factors associated with poor treatment outcome in Debre Tabor, May 2008–April 2013; N = 303
From: Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia
Variable | Treatment outcome | COR (95% CI) | P value | AOR (95% CI) | P value | |
|---|---|---|---|---|---|---|
Poor (%) | Successful (%) | |||||
Sex | ||||||
Male | 29 (74.4) | 144 (54.6) | 2.417 (1.132–5.160) | 0.023 | 2.516 (1.101–4.816)* | 0.029 |
Female | 10 (25.6) | 120 (45.4) | 1 | 1 | ||
Age group | ||||||
≤ 14 | 1 (2.6) | 19 (7.2) | 1 | 1 | 1 | |
15–24 | 7 (18.0) | 61 (23.1) | 10.0 (1.163–85.998) | 0.036 | 8.247 (0.723–94.052) | 0.089 |
25–34 | 6 (15.4) | 77 (29.2) | 4.586 (1.535–13.704) | 0.006 | 6.395 (1.741–23.492)* | 0.005 |
35–44 | 6 (15.4) | 41 (15.5) | 6.754 (2.182–20.905) | 0.001 | 15.157 (3.495–65.743)* | 0.000 |
45–54 | 6 (15.4 | 25 (9.5) | 3.596 (1.140–11.347) | 0.029 | 7.576 (1.791–32.052)* | 0.006 |
55–64 | 3 (7.7) | 22 (8.3) | 2.193 (0.677–7.100) | 0.190 | 4.850 (1.099–21.394)* | 0.037 |
≥ 65 | 10 (25.6) | 19 (7.2) | 3.86 (0.925–16.109) | 0.064 | 7.291 (1.409–37.735)* | 0.018 |
Residence | ||||||
Urban | 29 (74.4) | 158 (59.8) | 1.946 (0.91–4.159) | 0.086 | 3.214 (1.201–8.598)* | 0.020 |
Rural | 10 (25.6) | 106 (40.2) | 1 | 1 | ||
Baseline smear result | ||||||
Smear positive | 13 (33.3) | 68 (25.8) | 1 | |||
Smear negative | 26 (66.7) | 196 (74.2) | 1.441 (0.701–2.96) | 0.320 | ||
Smear result at 2nd month | ||||||
Negative | 4 (10.3) | 63 (23.9) | 1 | 1 | ||
Positive | 7 (17.9) | 3 (1.1) | 36.75 (6.792–198.842) | 0.000 | 40.132 (5.004–321.839)* | 0.001 |
Unknown | 28 (71.8) | 198 (75.0) | 16.50 (4.032–67.530) | 0.000 | 14.495 (2.409–87.236)* | 0.004 |
Type of TB | ||||||
Smear positive PTB | 13 (33.3) | 68 (25.8) | 1 | |||
Smear negative PTB | 11 (28.2) | 94 (35.6) | 0.769 (0.344–1.718) | 0.522 | ||
Extrapulmonary TB | 15 (38.5) | 102 (38.6) | 1.257 (0.55–2.873) | 0.588 | ||
HIV status | ||||||
Negative | 19 (48.7) | 160 (60.6) | 1 | |||
Positive | 6 (15.4) | 35 (13.3) | 1.184 (0.419–3.346) | 0.751 | 1.360 (0.208–8.910) | 0.748 |
Unknown | 14 (35.9) | 69 (26.1) | 1.709 (0.81–3.602) | 0.159 | 2.137 (0.338–11.394) | 0.387 |
Patient category | ||||||
New | 33 (84.6) | 234 (88.6) | 0.212 (0.071–0.633) | 0.005 | 0.168 (0.035–0.798)* | 0.025 |
Retreated | 6 (15.4) | 9 (3.4) | 1 | 1 | ||
Transferred in | 0 (00.0) | 17 (6.4) | – | |||
Unknown | 0 (00.0) | 4 (1.5) | – | |||
Year of treatment | ||||||
May 2008–April 2009 | 11 (28.2) | 55 (20.8) | 0.846 (0.349–2.052) | 0.712 | 0.707 (0.140–3.578) | 0.675 |
May 2009–April 2010 | 13 (33.3) | 55 (20.8) | 1.433 (0.491–4.186) | 0.510 | 0.616 (0.077–4.951) | 0.649 |
May 2010–April 2011 | 6 (15.4) | 43 (16.3) | 2.160 (0.703–6.632) | 0.178 | 1.228 (0.144–10.500) | 0.851 |
May 2011–April 2012 | 5 (12.8) | 54 (20.5) | 2.850 (0.856–9.489) | 0.088 | 2.453 (0.269–22.385) | 0.426 |
May 2012–April 2013 | 4 (10.3) | 57 (21.6) | 1 | 1 | ||