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Fig. 3 | BMC Research Notes

Fig. 3

From: An increased fraction of circulating miR-363 and miR-16 is particle bound in patients with chronic lymphocytic leukaemia as compared to normal subjects

Fig. 3

Distribution of selected miRNA between plasma protein and particle bound fractions of plasma. Between 31 and 37 plasma fractions were obtained by size exclusion chromatography from either healthy volunteers (panels to the left) or patients (panels to the right) as indicated on the x-axis. Fractions 1–13 are designated early particle containing fractions (grey shaded area). UniSp2 RNA spike-in was employed as a control and quantitative RT-PCR Ct values obtained are shown (red squares and right-y-axis). For each individual miRNA tested (mir-363, miR-16, miR142 and let-7a) the percentage of the total amount of miRNA in each fraction is plotted (blue squares and left-y-axis) of each individual graph. Percentage of total within fractions 1–13 is presented within the grey shaded area

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BMC Research Notes

ISSN: 1756-0500

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