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Table 2 Characteristics and management of 70 pneumococcal pneumonia cases diagnosed based on an initial comprehensive assessment at admission

From: The efficacy of high-dose penicillin G for pneumococcal pneumonia diagnosed based on initial comprehensive assessment at admission: an observational study

Characteristics

Totala

N = 70

Radiological characteristics

 Bilateral infiltrate

15 (21.4)

 Upper lobe infiltrate

10 (14.3)

 Pleural effusion

2 (2.8)

Microbial characteristics

 Gram stain

  GPC dominant (good-quality only)b

24 (34.3)

  GPC dominant (regardless of quality)

41 (58.6)

  Not performed

11 (15.7)

 Urine pneumococcal antigen

47 (67.1)

 Blood culture

  Streptococcus pneumoniae

5 (7.1)

  Streptococcus mitis

1 (1.4)

  Staphylococcus aureus

1 (1.4)

 Presumptive etiology

  Undetermined

17 (24.3)

  Streptococcus pneumoniae

46 (65.7)

  Other pathogens

7 (10.0)c

Pneumonia severity

 Pneumonia severity index

  Total score, median (IQR)

97.5 (77.3–121.0)

  Class 1

5 (7.1)

  Class 2

7 (10.0)

  Class 3

19 (27.1)

  Class 4

26 (37.1)

  Class 5

13 (18.6)

 CURB-65

  Low risk

22 (31.4)

  Intermediate risk

23 (32.9)

  High risk

25 (35.7)

Management during hospital stay

 Penicillin G treatment

  Continuous infusion

65 (92.9)

  Duration, day, median (IQR)

7.0 (4.3–7.0)

  Switch to oral amoxicillin

10 (14.3)

 Macrolide combination

0 (0.0)

 Corticosteroid use

2 (2.9)

 Tracheal intubation

1 (1.4)

 Vasopressor use

1 (1.4)

  1. aValues are shown as numbers (percentages) unless stated otherwise
  2. bSputum specimens were judged to be high quality if there were fewer than 10 squamous epithelial cells and greater than 10 polymorphonuclear cells per low-power field
  3. cThis value includes Haemophilus influenzae (four cases), Staphylococcus aureus (one case), Streptococcus mitis (one case), and Streptococcus agalactiae (one case)