Fig. 1

Body mass (a), food intake (b), and plasma levels of glucose (c), insulin (d), and IL-6 (e) by treatment group. *Significant difference between lean mice fed standard diet and mice fed HFSD (P < 0.05); ^†significant difference with mice fed HFSD (P < 0.05); ^‡significant difference between males and females given the same treatment (P < 0.05). LN, lean mice fed standard diet (n = 10 females, 8 males); HFSD, high-fat, high-sugar diet (n = 9 females, 9 males); Ex, exercise (n = 9 females, 10 males); Gen, genistein (n = 8 females, 8 males); GenEx, genistein and exercise (n = 10 females, 8 males). Data are expressed as mean ± 2 SE