Fig. 1

The effect of prone positioning on gas exchange and respiratory mechanics are shown in (a–c). a Line graph representing mean PaO2/FiO2 ratio before, during, and after prone positioning, n=20, b Line graph representing mean Aa gradient before, during, and after prone positioning, n = 20, (c) Line graph representing mean respiratory system static compliance (CRS) before, during, and after prone positioning, n = 15, (d) shows the association between respiratory system static compliance (CRS) and severity of SARS-CoV-2 ARDS. It displays a box plot representing the difference in baseline PF ratio between patients with <median CRS and > median CRS, n = 19. PF = PaO2/FiO2 ratio, Aa = Alveolar-arterial gradient, CRS = respiratory system static compliance. Pre-Prone = immediately prior to prone positioning, Prone 1 = following prone positioning, Prone 2 = the mid-point of prone positioning, Prone 3 = prior to supination, and Post-Prone = following supination. Statistical Analysis: Analyzed by repeated measures two-way ANOVA with Tukey’s post-hoc test for multiple comparisons for line graphs and Mann-Whitney U test for box plot. ****P<0.0001, ** P<0.01, * P<0.05. Patients with incomplete data sets were excluded from analysis. a–c: error bars represent standard deviation. d: box plot with bars representing range.