Fig. 1

Immunostaining for CD138 (a, c, e, g, i, k) and Kappa (b, d, f, h, j, l) markers in B6 mouse tissues. a, b Small intestinal Peyer’s patches had plasmacyte immunostaining (arrows) for both markers. c, d Small intestine wall. Plasmacytes (arrows and inset) were immunostained in lamina propria of villi for both markers. e Liver. CD138 immunostaining was localized in a sinusoidal pattern along with immunostaining of hepatocytes and biliary duct epithelium (arrow, inset). f Liver. Kappa immunostaining was negative (inset). g Kidney. Widespread CD138 immunostaining was seen in cortex(C), medulla (M), papilla (P) and pelvis (Pe) regions. h Kappa immunostaining was negative. i, j Renal glomeruli (highlighted by red arrows) had immunostaining of cells (black arrows). k Skin. CD138 immunostaining of epidermal (black arrow) and follicular epithelium (red arrow). l Skin. Kappa was negative immunostaining. DAB chromogen (brown color) and hematoxylin counter stain (blue color), bar = 250 µm (e–h, k, l), 125 µm (c, d), and 62 µm (a, b, i, j)