Determine the factors affecting the time to recovery of children with bacterial meningitis at Jigjiga university referral hospital in the Somali Regional State of Ethiopia: using the parametric shared frailty and AFT models

Table 4 Multivariable analysis using lognormal inverse Gaussian frailty model

Variable names	Category	Coefficient	S.E	ϕ	95% CI	P-value
Sex	Female(ref.)			1.00
Sex	Male	− 0.079	0.033	0.924	[0.866, 0.984]	0.014*
Age	< 1 month
	1–12 months	0.340	0.213	1.405	[0.926, 2.133]	0.110
	13–36 months	0.323	0.215	1.381	[0.906, 2.105]	0.130
	37–60 months	0.299	0.219	1.349	[0.878, 2.072]	0.170
	> 60 months	0.484	0.215	1.623	[1.065,2.4747]	0.024*
Vaccination status	No vaccinated(ref.)
Vaccination status	Yes vaccinated	− 0.109	0.037	0.898	[0.834, 0.965]	0.003*
Presence of comorbidity	Yes (ref.)
Presence of comorbidity	No	0.087	0.033	1.098	[1.022, 1.164]	0.008*
Breast feeding of patients	Yes (ref.)
Breast feeding of patients	No	0.484	0.215	0.616	(0.404, 0.939)	0.024*
Drug regime	Ceftriaxone plus vancomycin
	Ceftrazidime plus vancomycin	− 0.045	0.066	0.956	(0.839, 1.089)	0.500
	Ceftriaxone plus dexamethasone	− 0.070	0.042	0.932	(0.850, 1.012)	0.092
	Cefoperatone plus sulbactan	− 0.064	0.104	0.938	(0.765, 1.151)	0.450
	Ciprooxacin plus ceftriaxone	− 0.135	0.296	0.874	(0.489, 1.559)	0.650
	Ampicillin plus gentamycin	− 0.128	0.052	0.880	(0.795, 0.974)	0.013*
	Others	0.060	0.116	1.062	(0.846, 1.332)	0.600
	Constant	2.330	0.215	10.282	(6.742, 15.680)	0.000

p = 0.05 was statistically significant. ϴ = 0.98 ρ = 2.184 τ = 0.221 AIC = 2674.080 ϕ Acceleration Factor, CI Confidence Interval, ϴ Variance of random effect, τ Kendall’s Tau S.E standard error, Ref Reference. p Shape parameter, AIC Akaiks Information Criteria
*The significant variable at 5% level

ISSN: 1756-0500