Table 1 MIC, MFC and MTT test results

Candida albicans

Carvacrol

22.87 ± 7.5

44.38 ± 14.29

49.97 ± 8.82

Nystatin

81.67 ± 40.81

160.78 ± 82.35

30.75 ± 10.5

Nystatin + Carvacrol

39.31 ± 21.17

80.56 ± 44.58

78.41 ± 11.34

p-value

< 0.001

< 0.001

< 0.001

Candida glabrata

Carvacrol

27.30 ± 6.88

52.19 ± 13.77

50.2 ± 9.33

Nystatin

80.24 ± 24.17

160 ± 49

31.2 ± 10.7

Nystatin + Carvacrol

40.91 ± 22.25

82 ± 44

76 ± 10

p-value

Not significant

Not significant

Not significant

Candida krusei

Carvacrol

28.71 ± 4.89

56.25 ± 8.79

43.93 ± 8.24

Nystatin

75.83 ± 20.10

145 ± 43

35.3 ± 8.2

Nystatin + Carvacrol

49.76 ± 16.81

99 ± 22

77 ± 10

p-value

Not significant

Not significant

Not significant

Candida tropicalis

Carvacrol

25.47 ± 5.21

49.8 ± 10.77

53.51 ± 15.88

Nystatin

74.78 ± 24.8

146 ± 45

29.6 ± 9.7

Nystatin + Carvacrol

31.56 ± 13.49

63 ± 28

81 ± 10

p-value

Not significant

Not significant

Not significant

Candida (glabrata + krusei + tropicalis)

Carvacrol

27.13 ± 6.36

52.25 ± 12.68

50.04 ± 10.76

Nystatin

78.69 ± 23.49

155 ± 47

31.4 ± 10.2

Nystatin + Carvacrol

40.27 ± 20.63

80 ± 41

77 ± 10

p-value

< 0.001

< 0.001

< 0.001

All species

Carvacrol

24.96 ± 7.25

48.23 ± 14.03

50.01 ± 9.77

Nystatin

80.21 ± 33.33

158 ± 67

31.1 ± 10.3

Nystatin + Carvacrol

39.78 ± 20.81

81 ± 43

78 ± 11

p-value

< 0.001

< 0.001

< 0.001